Journal Reviews
Two-year GATHER2 data: anatomical gains, functional questions for avacincaptad pegol in geographic atrophy
Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) remains a leading cause of irreversible central vision loss, and complement dysregulation has long been implicated in its pathogenesis. In 2023, the US FDA approved the first two GA therapies, both...
ROCK inhibition after descemetorhexis without endothelial keratoplasty: a small but timely Indian RCT
The authors present a single-centre, prospective, randomised, comparative clinical trial (RCT) of 24 eyes of 24 patients with mild-to-moderate Fuchs endothelial corneal dystrophy (FECD) undergoing combined phacoemulsification and a standardised 4mm central descemetorhexis without endothelial keratoplasty (DWEK), with or without...
Seeing mitochondrial disease
This review highlights mitochondrial diseases as the most common inherited neurometabolic disorders, often affecting multiple high-energy organs, with eye involvement frequently representing the earliest or predominant feature. Diagnosis is challenging due to significant genetic and clinical heterogeneity, including variable expressivity,...
Healthcare access gaps in adults with vision difficulty
The authors analyse data from the Behavioral Risk Factor Surveillance System (2019–2021) to evaluate disparities in healthcare access among adults with self-reported vision difficulty. This large cross-sectional study demonstrates that individuals reporting visual impairment face significant barriers across multiple domains...
Trial of low-concentration bimatoprost and timolol eye gel versus higher concentrations
This is an international, multicentre, randomised, parallel group, investigator-masked study of 554 patients, having insufficient control of intraocular pressure (IOP) with a first-line monotherapy and requiring dual therapy. Two hundred and eighty patients were randomised to receive low concentration (BTFCEG...
Use of AI apps in providing information about paediatric ophthalmology
The authors evaluated the reliability and accuracy of responses given by 3 AI apps to questions related to paediatric ophthalmology. One-hundred multiple choice questions specific to paediatric ophthalmology were selected from the OphthoQuestions questionnaire bank (4551 questions on this platform)....
To involve or not to involve parents in the RoP examination of infants
This study investigated whether allowing parents to witness retinopathy of prematurity (RoP) examinations influences their levels of anxiety, depression and hopelessness, in addition to potential differences in psychological outcomes between parents of infants with and without RoP, and between fathers...
Normative data values for childhood corneal sensitivity
The authors aimed to establish normative data regarding corneal sensitivity in a paediatric age group. They included 122 right eyes of 122 children with mean age of 11.29 ±4.6 years (aged 5–18 years); 63 female and 59 male. Bilateral corneal...
Randomised controlled trial of Tecnis intraocular lenses for paediatric cataract
This was a prospective randomised study comparing visual acuity (at distance, intermediate and near), depth of focus and quality of vision in paediatric patients undergoing cataract surgery with implantation of a new monofocal Tecnis Eyhance ICB00 intraocular lens (IOL) vs...
Association between smartwatch usage and myopia progression
This is a study exploring the association of smart watch usage in children aged 11–13 and myopia in a Chinese cohort of 526 students. The authors present data showing high daily smartwatch usage (>1hour) showed more myopic shift (-0.95) and...
Choroidal and retinal vascular changes after horizontal rectus surgery
The authors used wide field swept-source OCT angiography (SSOCTA) to evaluate changes in retinal and choroidal blood flow before and after horizontal rectus muscle surgery. They aimed to characterise the haemodynamic impact of extraocular muscle surgery on the posterior pole...
Difference in anterior ciliary vessels across horizontal and vertical rectus muscles
In order to obtain more information about anterior ciliary vessels (ACVs), the authors compared bilateral ACVs of the lateral and medial recti muscles and intraoperative observations of the difference of AVC preservation between the lateral rectus and other rectus muscles....
